Epithalon (Epitalon, Ala-Glu-Asp-Gly) is a synthetic tetrapeptide developed from research into the pineal gland extract Epithalamin by Russian scientist Vladimir Khavinson. With a molecular weight of 390.35 g/mol, it has been investigated as a bioregulatory peptide with possible interactions with telomerase activity and melatonin production.

Research literature, primarily from Russian and Eastern European institutions, has examined Epithalon in models of aging, immune senescence, and circadian disruption. Key findings centered on its apparent ability to activate telomerase in somatic cells, an area of significant ongoing interest in longevity science.

Each Etched Research vial contains 10mg of lyophilized powder, purity-verified at ≥99% via HPLC and mass spectrometry. Batch-specific Certificate of Analysis included.

Specifications:
– Molecular Formula: C₁₄H₂₂N₄O₉
– Molecular Weight: 390.35 g/mol
– Sequence: Ala-Glu-Asp-Gly
– Purity: ≥99% (HPLC + Mass Spectrometry)
– Form: Lyophilized powder
– Storage: -20°C (lyophilized); 4°C once reconstituted, use within 30 days

FOR IN VITRO RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION, INGESTION, OR ANY IN VIVO USE.

Research at a Glance

What it is: A synthetic four-amino-acid peptide modeled on a pineal-gland extract, studied in aging and telomere research.
Researchers have studied it for: Telomere length and telomerase activity, lifespan and aging markers in animals, and pineal/circadian signaling.
Evidence level: Thin. Mostly older Russian lab and animal work, plus a couple of recent cell studies. No solid human longevity trials.
The short version: Epithalon is a longevity-lane peptide with a big story and a small evidence base. Most of what researchers have published comes from Russian animal and cell studies, with very little independent Western confirmation. Read the claims with both eyes open.

Read the research →