SS-31 10mg lyophilized research peptide vial
SS-31 | 10mg - Image 2

SS-31 | 10mg

$65.00

Mitochondria-targeted tetrapeptide (elamipretide). Selectively concentrates in inner mitochondrial membrane. Studied for cardioprotection and oxidative stress.

Availability: 14 in stock

SKU: SS-31-10mg-ER Category:
Third-party COA — View Sample

SS-31 (Elamipretide, D-Arg-2’6′-Dmt-Lys-Phe-NH2) is a synthetic tetrapeptide developed by Hazel Szeto that selectively targets the inner mitochondrial membrane via electrostatic interaction with cardiolipin. At a molecular weight of 640.84 g/mol, it is notable for its alternating aromatic-cationic structure, which confers both membrane permeability and antioxidant activity.

Research has examined SS-31 in models of ischemia-reperfusion injury, heart failure, skeletal muscle aging, and neurodegenerative conditions, with attention to its capacity to reduce mitochondrial ROS production without uncoupling oxidative phosphorylation. It represents a rare class of compounds that act directly at the site of electron transport dysfunction.

Each Etched Research vial contains 10mg of lyophilized powder.

Specifications:
– Molecular Formula: C32H49N9O5
– Molecular Weight: 640.78 g/mol
– Sequence: D-Arg-2’6′-Dmt-Lys-Phe-NH2

– Form: Lyophilized powder
– Storage: -20°C (lyophilized); 4°C once reconstituted, use within 30 days

FOR IN VITRO RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION, INGESTION, OR ANY IN VIVO USE.

Research at a Glance
  • What it is: A lab-made peptide built to reach inside mitochondria (also called elamipretide or MTP-131).
  • Researchers have studied it for: rare mitochondrial myopathy, Barth syndrome, and heart failure with reduced pumping strength.
  • Evidence level: Real human trials, which is rare here, but a mixed record. The two larger trials (MMPOWER-3 and PROGRESS-HF) did not hit their main goals. The positive readouts came from a short 5-day trial and a very small long-term group.
  • The short version: SS-31 has more human trial data than most in this category, but the record is mixed rather than a clean win. Nearly all of it ran in people with rare mitochondrial or heart disease, not healthy adults. This is a research summary, not a reason to use anything.

Read the research →

Format

Single vial

Frequently asked questions

Does the product come with instructions?

No. Etched supplies research materials, not use instructions. Each vial ships labeled with the compound name, the labeled amount, and the lot number, and that is what comes in the box. Etched does not provide instructions for use, dosing, or administration for any product, on the label, on this page, or by email. General laboratory handling notes (storage, what bacteriostatic water is) are on the FAQ page at https://etchedresearch.com/faq/. All products are sold for research use only, not for human consumption.

What is the amount of peptide in this product?

The label reads SS-31 10mg. That figure is the labeled net quantity of SS-31 in the vial, supplied as lyophilized (freeze-dried) powder. It is not the weight of the vial and not a reconstituted volume. Where a Janoshik Analytical report exists for a lot, the measured result for that lot is on the report itself, and the reports that exist are listed on the COA page at https://etchedresearch.com/coa/. Etched ships lyophilized powder only.

Are additional supplies needed?

Nothing else is included, and Etched sells the lyophilized compound only. Bacteriostatic water is sterile water with a small amount of benzyl alcohol added, used in laboratory settings to reconstitute lyophilized (freeze-dried) research peptides into solution. Etched does not sell bacteriostatic water as a product. It is described here only to explain the reconstitution step in a research context. Any supplies a laboratory setting requires are sourced by the researcher.

How is purity verified?

By a third-party laboratory, named. Janoshik Analytical confirms compound identity by mass spectrometry and measures purity by HPLC. Etched does not use vague "third-party tested" language without naming the lab. The measured number for a tested lot is on that lot's report, not a mood word. Where a Janoshik report exists for a compound it is listed on the COA page at https://etchedresearch.com/coa/, and the report itself carries the lot number and the measured purity. Not every listing has a report posted yet, and the COA page shows which do.

Where do products ship from?

Etched ships within the United States only. There is no international shipping. Orders are fulfilled domestically from within the USA. Orders ship in plain, unmarked packaging with no indication of the contents on the outside.

Who is eligible to purchase?

Etched sells to buyers who are 21 years of age or older and who are qualified researchers, research professionals, or affiliated with a research institution, purchasing for in vitro laboratory research. Every order requires an attestation to those three points at checkout, and the order will not process without it. Research Use Only (RUO) means a product is sold only as a material for laboratory and research use. RUO compounds are not drugs, are not approved by the FDA for human consumption, and are not sold or intended for personal use. Shipping is to United States addresses only.

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