MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid mitochondria-derived peptide (MDP) encoded within the mitochondrial genome, a relatively recent discovery that has reshaped understanding of mitochondria as active endocrine signaling organs rather than passive energy producers.
Research has focused on MOTS-c’s role in AMPK activation, glucose and fatty acid metabolism, insulin sensitivity, and exercise-mimetic signaling. Studies published in the journal Cell Metabolism identified its ability to regulate the folate cycle and methionine metabolism, placing it at the intersection of metabolic homeostasis and cellular stress response.
Each Etched Research vial contains 10mg of lyophilized powder, purity-verified at ≥99% via HPLC and mass spectrometry. Batch-specific Certificate of Analysis included.
Specifications:
– Molecular Formula: C95H157N27O28S2
– Molecular Weight: 2174.47 g/mol
– Sequence: MRWQEMGYIFYPRKLR
– Purity: ≥99% (HPLC + Mass Spectrometry)
– Form: Lyophilized powder
– Storage: -20°C (lyophilized); 4°C once reconstituted, use within 30 days
FOR IN VITRO RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION, INGESTION, OR ANY IN VIVO USE.




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