ARA-290 10mg

$79.00

Available for pre-order

SKU: ARA-290-10mg-ER Category:
Ships as lyophilized powder — not reconstituted

ARA-290 (Cibinetide, Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser) is a synthetic 11-mer peptide engineered from the helix-B surface domain of erythropoietin, developed to selectively activate the Innate Repair Receptor (a heterodimer of EPOR and CD131) without triggering EPO’s effect on red blood cell production. At a molecular weight of approximately 1257.4 g/mol, it is structurally distinct from full-length EPO and acts through a separate, tissue-protective signaling pathway.

Research has examined ARA-290 in two human trials in sarcoidosis-associated small fiber neuropathy, plus mechanism studies in inflammation and wound-healing models, with attention to its effects on corneal nerve fiber density and inflammatory signaling through CD131/JAK2 and NF-kB p65 inhibition.

Each Etched Research vial contains 10mg of lyophilized powder.

Specifications:
– Molecular Formula: C55H82N18O18
– Molecular Weight: ~1257.4 g/mol
– Sequence: Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
– CAS Number: 1208243-50-8
– PubChem CID: 91810664
– InChIKey: WZTIQQBMSJTRBR-WYKNNRPVSA-N

– Form: Lyophilized powder
– Storage: -20°C (lyophilized); 4°C once reconstituted, use within 30 days

FOR IN VITRO RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION, INGESTION, OR ANY IN VIVO USE.

Research at a Glance
  • What it is: A peptide engineered from erythropoietin, built to activate a tissue-protective signaling pathway without EPO’s effect on red blood cells.
  • Researchers have studied it for: sarcoidosis-associated small fiber neuropathy, in two human trials, plus mechanism work in inflammation and wound-healing research models.
  • Evidence level: Real human trial data exists, in one specific rare-disease population. The company that ran those trials, Araim Pharmaceuticals, has since ceased operations, and no Phase III trial was ever completed.
  • The short version: ARA-290 has real, published human trial data behind it, which is genuinely uncommon in this category. That data is narrow, one disease population, one structural endpoint, and a development program that stopped before full approval. This is a research summary, not a reason to use anything.

Read the research →

Frequently asked questions

Does the product come with instructions?

No. Etched supplies research materials, not use instructions. Each vial ships labeled with the compound name, the labeled amount, and the lot number, and that is what comes in the box. Etched does not provide instructions for use, dosing, or administration for any product, on the label, on this page, or by email. General laboratory handling notes (storage, what bacteriostatic water is) are on the FAQ page at https://etchedresearch.com/faq/. All products are sold for research use only, not for human consumption.

What is the amount of peptide in this product?

The amount printed on the label is the labeled net quantity of compound in each vial, supplied as lyophilized (freeze-dried) powder. It is not the weight of the vial and not a reconstituted volume. Where a Janoshik Analytical report exists for a lot, the measured result for that lot is on the report itself, and the reports that exist are listed on the COA page at https://etchedresearch.com/coa/. Etched ships lyophilized powder only.

Are additional supplies needed?

Nothing else is included, and Etched sells the lyophilized compound only. Bacteriostatic water is sterile water with a small amount of benzyl alcohol added, used in laboratory settings to reconstitute lyophilized (freeze-dried) research peptides into solution. Etched does not sell bacteriostatic water as a product. It is described here only to explain the reconstitution step in a research context. Any supplies a laboratory setting requires are sourced by the researcher.

How is purity verified?

By a third-party laboratory, named. Janoshik Analytical confirms compound identity by mass spectrometry and measures purity by HPLC. Etched does not use vague "third-party tested" language without naming the lab. The measured number for a tested lot is on that lot's report, not a mood word. Where a Janoshik report exists for a compound it is listed on the COA page at https://etchedresearch.com/coa/, and the report itself carries the lot number and the measured purity. Not every listing has a report posted yet, and the COA page shows which do.

Where do products ship from?

Etched ships within the United States only. There is no international shipping. Orders are fulfilled domestically from within the USA. Orders ship in plain, unmarked packaging with no indication of the contents on the outside.

Who is eligible to purchase?

Etched sells to buyers who are 21 years of age or older and who are qualified researchers, research professionals, or affiliated with a research institution, purchasing for in vitro laboratory research. Every order requires an attestation to those three points at checkout, and the order will not process without it. Research Use Only (RUO) means a product is sold only as a material for laboratory and research use. RUO compounds are not drugs, are not approved by the FDA for human consumption, and are not sold or intended for personal use. Shipping is to United States addresses only.

Scroll to Top