About P21
P21 is a synthetic peptide derived from a region of ciliary neurotrophic factor (CNTF). It was developed as a research tool for studying neurogenesis and cognitive enhancement in preclinical models. P21 retains the neurogenic activity of CNTF without binding to the CNTF receptor, allowing researchers to study downstream neurotrophic effects more selectively.
Research Applications
P21 has been studied primarily in rodent cognitive models. Reported findings include increased BDNF expression in hippocampal tissue, enhanced neurogenesis in the dentate gyrus, and improved performance on standardized memory tasks. The peptide crosses the blood-brain barrier in animal models, making it relevant for CNS research.
For in vitro research use only. Not for human or veterinary use, therapeutic, or diagnostic purposes.
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