Retatrutide | 10mg

$85.00

Triple GLP-1/GIP/glucagon receptor agonist. Phase 2 human data exists, mid-stage.

Availability: 15 in stock

SKU: RT10-ER Category:
Third-party COA — View Sample

Retatrutide (LY3437943) is a triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously, with a molecular weight of approximately 5052.9 g/mol. It sits at the frontier of incretin-based metabolic research, with Phase 2 clinical trial data showing differentiated outcomes compared to single and dual agonists.

The addition of glucagon receptor agonism to the GLP-1/GIP dual mechanism creates a tripartite action on energy homeostasis: incretin-mediated insulin secretion, appetite regulation, and direct stimulation of hepatic fatty acid oxidation and thermogenesis. For researchers investigating the comparative pharmacology of incretin receptor systems, retatrutide enables the study of all three pathways in a single compound.

Each Etched Research vial contains 10mg of lyophilized powder.

Specifications:
– Molecular Weight: ~5052.9 g/mol
– Form: Lyophilized powder
– Storage: -20°C, lyophilized, sealed

FOR IN VITRO RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION, INGESTION, OR ANY IN VIVO USE.

Research at a Glance
  • What it is: A lab-made molecule (also called LY3437943) that switches on three hormone receptors at once: GLP-1, GIP, and glucagon.
  • Researchers have studied it for: Body weight in obesity, blood sugar (HbA1c) in type 2 diabetes, and liver fat.
  • Evidence level: Phase 2 human trials exist, meaning mid-stage.
  • The short version: Retatrutide is one of the newest metabolic compounds, and it already has real phase 2 human data. Researchers recorded large drops in body weight, blood sugar, and liver fat within specific patient groups over under a year. It is still investigational with no approval, the trials logged mostly gut-related side effects, and none of this is a safety conclusion.

Read the research →

Format

Single vial

Frequently asked questions

Does the product come with instructions?

No. Etched supplies research materials, not use instructions. Each vial ships labeled with the compound name, the labeled amount, and the lot number, and that is what comes in the box. Etched does not provide instructions for use, dosing, or administration for any product, on the label, on this page, or by email. General laboratory handling notes (storage, what bacteriostatic water is) are on the FAQ page at https://etchedresearch.com/faq/. All products are sold for research use only, not for human consumption.

What is the amount of peptide in this product?

The label reads Retatrutide 10mg. That figure is the labeled net quantity of Retatrutide in the vial, supplied as lyophilized (freeze-dried) powder. It is not the weight of the vial and not a reconstituted volume. Where a Janoshik Analytical report exists for a lot, the measured result for that lot is on the report itself, and the reports that exist are listed on the COA page at https://etchedresearch.com/coa/. Etched ships lyophilized powder only.

Are additional supplies needed?

Nothing else is included, and Etched sells the lyophilized compound only. Bacteriostatic water is sterile water with a small amount of benzyl alcohol added, used in laboratory settings to reconstitute lyophilized (freeze-dried) research peptides into solution. Etched does not sell bacteriostatic water as a product. It is described here only to explain the reconstitution step in a research context. Any supplies a laboratory setting requires are sourced by the researcher.

How is purity verified?

By a third-party laboratory, named. Janoshik Analytical confirms compound identity by mass spectrometry and measures purity by HPLC. Etched does not use vague "third-party tested" language without naming the lab. The measured number for a tested lot is on that lot's report, not a mood word. Where a Janoshik report exists for a compound it is listed on the COA page at https://etchedresearch.com/coa/, and the report itself carries the lot number and the measured purity. Not every listing has a report posted yet, and the COA page shows which do.

Where do products ship from?

Etched ships within the United States only. There is no international shipping. Orders are fulfilled domestically from within the USA. Orders ship in plain, unmarked packaging with no indication of the contents on the outside.

Who is eligible to purchase?

Etched sells to buyers who are 21 years of age or older and who are qualified researchers, research professionals, or affiliated with a research institution, purchasing for in vitro laboratory research. Every order requires an attestation to those three points at checkout, and the order will not process without it. Research Use Only (RUO) means a product is sold only as a material for laboratory and research use. RUO compounds are not drugs, are not approved by the FDA for human consumption, and are not sold or intended for personal use. Shipping is to United States addresses only.

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