KPV | 10mg

$45.00

Alpha-MSH-derived tripeptide (Lys-Pro-Val). Studied for anti-inflammatory effects and gut barrier integrity. High stability profile.

Availability: 1 in stock

SKU: KPV-10mg-ER Category:
Third-party COA — View Sample

KPV (Lysine-Proline-Valine) is a C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (alpha-MSH). Despite its small size, a molecular weight of just 341.43 g/mol, it has attracted significant research attention for its interactions with melanocortin receptors and downstream inflammatory signaling pathways.

Research literature has examined KPV’s potential role in intestinal epithelial function, cytokine modulation, and skin barrier models. Its tripeptide structure enables rapid cellular uptake, making it a practical compound for in-vitro and in-vivo inflammatory response studies.

Each Etched Research vial contains 10mg of lyophilized powder.

Specifications:
– Molecular Formula: C16H30N4O4
– Molecular Weight: 341.43 g/mol
– Sequence: Lys-Pro-Val

– Form: Lyophilized powder
– Storage: -20°C (lyophilized); 4°C once reconstituted, use within 30 days

FOR IN VITRO RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION, INGESTION, OR ANY IN VIVO USE.

Research at a Glance
  • What it is: A three-amino-acid peptide (Lys-Pro-Val) that makes up the tail end of the natural hormone alpha-MSH, studied for anti-inflammatory activity.
  • Researchers have studied it for: intestinal inflammation and colitis in animal models, how it quiets inflammatory signals in gut and immune cells, and how the body takes it in through a transporter called PepT1.
  • Evidence level: Animal and in-vitro (lab-dish) models. No large independent human trials.
  • The short version: KPV is the small tail piece of alpha-MSH, and researchers have studied it mostly in mice and cell cultures to see how it lowers inflammation in the gut. Across those colitis models it lowered inflammatory markers and eased tissue damage. This is a summary of what researchers observed in their models, not a claim about what it does for a person.

Read the research →

Format

Single vial

Frequently asked questions

Does the product come with instructions?

No. Etched supplies research materials, not use instructions. Each vial ships labeled with the compound name, the labeled amount, and the lot number, and that is what comes in the box. Etched does not provide instructions for use, dosing, or administration for any product, on the label, on this page, or by email. General laboratory handling notes (storage, what bacteriostatic water is) are on the FAQ page at https://etchedresearch.com/faq/. All products are sold for research use only, not for human consumption.

What is the amount of peptide in this product?

The label reads KPV 10mg. That figure is the labeled net quantity of KPV in the vial, supplied as lyophilized (freeze-dried) powder. It is not the weight of the vial and not a reconstituted volume. Where a Janoshik Analytical report exists for a lot, the measured result for that lot is on the report itself, and the reports that exist are listed on the COA page at https://etchedresearch.com/coa/. Etched ships lyophilized powder only.

Are additional supplies needed?

Nothing else is included, and Etched sells the lyophilized compound only. Bacteriostatic water is sterile water with a small amount of benzyl alcohol added, used in laboratory settings to reconstitute lyophilized (freeze-dried) research peptides into solution. Etched does not sell bacteriostatic water as a product. It is described here only to explain the reconstitution step in a research context. Any supplies a laboratory setting requires are sourced by the researcher.

How is purity verified?

By a third-party laboratory, named. Janoshik Analytical confirms compound identity by mass spectrometry and measures purity by HPLC. Etched does not use vague "third-party tested" language without naming the lab. The measured number for a tested lot is on that lot's report, not a mood word. Where a Janoshik report exists for a compound it is listed on the COA page at https://etchedresearch.com/coa/, and the report itself carries the lot number and the measured purity. Not every listing has a report posted yet, and the COA page shows which do.

Where do products ship from?

Etched ships within the United States only. There is no international shipping. Orders are fulfilled domestically from within the USA. Orders ship in plain, unmarked packaging with no indication of the contents on the outside.

Who is eligible to purchase?

Etched sells to buyers who are 21 years of age or older and who are qualified researchers, research professionals, or affiliated with a research institution, purchasing for in vitro laboratory research. Every order requires an attestation to those three points at checkout, and the order will not process without it. Research Use Only (RUO) means a product is sold only as a material for laboratory and research use. RUO compounds are not drugs, are not approved by the FDA for human consumption, and are not sold or intended for personal use. Shipping is to United States addresses only.

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